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Home >> Antibodies >> Alpha-2-macroglobulin Antibody

Alpha-2-macroglobulin Antibody (F44165)

  Catalog No Formulation Size Price (USD)  
Image F44165-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F44165-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Alpha-2-macroglobulin antibody western blot analysis in mouse plasma lysate. Predicted molecular weight: ~163/200kDa (unmodified/glycosylated).
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Bovine
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P01023
Applications Western blot : 1:1000
Limitations This Alpha-2-macroglobulin antibody is available for research use only.
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Description

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].

Application Notes

Titration of the Alpha-2-macroglobulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 93-120 from the human protein was used as the immunogen for this Alpha-2-macroglobulin antibody.

Storage

Aliquot the Alpha-2-macroglobulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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