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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The ALAS1 gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate.
Optimal dilution of the ALAS1 antibody should be determined by the researcher.
A synthetic peptide specific to human ALAS1 was used as the immunogen for the ALAS1 antibody.
Store the ALAS1 antibody at -20oC.
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