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Home >> Antibodies >> ADAMTS13 Antibody

ADAMTS13 Antibody (F50404)

  Catalog No Formulation Size Price (USD)  
Image F50404-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F50404-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
IHC analysis of FFPE human hepatocarcinoma with ADAMTS13 antibody
Western blot analysis of ADAMTS13 antibody and CEM lysate.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q76LX8
Localization Cytoplasmic
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This ADAMTS13 antibody is available for research use only.
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Description

ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.

Application Notes

Titration of the ADAMTS13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 829-858 from the human protein was used as the immunogen for this ADAMTS13 antibody.

Storage

Aliquot the ADAMTS13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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