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- Tel: 858.663.9055
- Email: info@nsjbio.com
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ACE2 is a carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses. [UniProt]
Titration of the ACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 140-172 from the human protein was used as the immunogen for this ACE2 antibody.
Aliquot the ACE2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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