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Home >> Antibodies >> ACE2 Antibody

ACE2 Antibody (F49433)

  Catalog No Formulation Size Price (USD)  
Image F49433-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F49433-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot analysis of lysate from human kidney tissue lysate using ACE2 antibody diluted at 1:1000. Predicted molecular weight: 90-100 kDa.
IHC analysis of FFPE human breast carcinoma tissue stained with the ACE2 antibody
Flow cytometric analysis of HL-60 cells using ACE2 antibody (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q9BYF1
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This ACE2 antibody is available for research use only.
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Description

ACE2 is a carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses. [UniProt]

Application Notes

Titration of the ACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 140-172 from the human protein was used as the immunogen for this ACE2 antibody.

Storage

Aliquot the ACE2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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