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- Tel: 858.663.9055
- Email: info@nsjbio.com
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4- nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
The stated application concentrations are suggested starting points. Titration of the UGT2B4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Recombinant human protein was used as the immunogen for the UGT2B4 antibody.
Aliquot the UGT2B4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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