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- Tel: 858.663.9055
- Email: info@nsjbio.com
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq].
Titration of the TBR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 52-80 from the human protein was used as the immunogen for this TBR1 antibody.
Aliquot the TBR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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