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Home >> Antibodies >> RAX Antibody

RAX Antibody (N1107)

  Catalog No Formulation Size Price (USD)  
Image N1107-100UG 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 429
Image
N1107-25UG 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 25 ug 219
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Western blot testing of human samples with RAX antibody at 1ug/ml.
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Protein A affinity chromatography
Buffer 1X PBS, pH 7.4
Gene ID 30062
Applications Western blot : 1-3ug/ml
Limitations This RAX antibody is available for research use only.
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Description

Rax (Retinal and anterior neural fold homeobox), a paired-type homeobox protein, is a human homolog of Drosophila Rx protein. It is a marker of developing eye and forebrain in vertebrates, initially expressed in the region of the forebrain where optic vesicles are formed, and is involved in promoting the division of retinal progenitor cells early in development. As development progresses, expression is seen in the retina and hypothalamus. RAX is essential for eye development. Knockout of RAX in mice eliminated eye development, and RAX mutation in humans result in Anophthalmia, where one or both eyes fail to develop.

Application Notes

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Immunogen

A recombinant protein fragment from the C-terminus of human RAX was used as the immunogen for this antibody.

Storage

Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Alternate Names

Retina and anterior neural fold homeobox antibody

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