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- Tel: 858.663.9055
- Email: info@nsjbio.com
Rax (Retinal and anterior neural fold homeobox), a paired-type homeobox protein, is a human homolog of Drosophila Rx protein. It is a marker of developing eye and forebrain in vertebrates, initially expressed in the region of the forebrain where optic vesicles are formed, and is involved in promoting the division of retinal progenitor cells early in development. As development progresses, expression is seen in the retina and hypothalamus. RAX is essential for eye development. Knockout of RAX in mice eliminated eye development, and RAX mutation in humans result in Anophthalmia, where one or both eyes fail to develop.
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
A recombinant protein fragment from the C-terminus of human RAX was used as the immunogen for this antibody.
Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Retina and anterior neural fold homeobox antibody
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