- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Pyruvate Kinase PKM Antibody / PKM2 (F54909)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54909-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F54909-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P14618 |
| Localization | Cytoplasmic, nuclear |
| Applications | Flow cytometry : 1:10-1:50 (1x10e6 cells) Immunohistochemistry (FFPE) : 1:50-1:100 Western blot : 1:500-1:1000 |
| Limitations | This Pyruvate Kinase PKM antibody is available for research use only. |
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PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
The stated application concentrations are suggested starting points. Titration of the Pyruvate Kinase PKM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 383-417 from the human protein was used as the immunogen for the Pyruvate Kinase PKM antibody.
Aliquot the Pyruvate Kinase PKM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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