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Home >> Antibodies >> PSMA1 Antibody

PSMA1 Antibody (F43982)

  Catalog No Formulation Size Price (USD)  
Image F43982-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F43982-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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PSMA1 antibody western blot analysis in A2058 lysate. Predicted molecular weight ~30 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine, Primate
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P25786
Localization Cytoplasmic, nuclear
Applications Western blot : 1:1000
Limitations This PSMA1 antibody is available for research use only.
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Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Application Notes

Titration of the PSMA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 234-262 from the human protein was used as the immunogen for this PSMA1 antibody.

Storage

Aliquot the PSMA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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