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Home >> Antibodies >> Plakophilin 2 Antibody

Plakophilin 2 Antibody (R31402)

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  Catalog No Formulation Size Price (USD)  
Image R31402 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of Plakophilin 2 antibody and Lane 1: rat heart; 2: human placenta; 3: (r) brain; 4: (r) intestine; 5: (h) HeLa; 6: (h) Jurkat; 7: (h) 293T; 8: (h) MCF-7; 9: (h) U87 lysate. Predicted molecular weight: 93-97 kDa.
Western blot testing of Plakophilin 2 antibody and Lane 1: rat heart; 2: human placenta; 3: (r) brain; 4: (r) intestine; 5: (h) HeLa; 6: (h) Jurkat; 7: (h) 293T; 8: (h) MCF-7; 9: (h) U87 lysate. Predicted molecular weight: 93-97 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q99959
Applications Western blot : 0.5-1ug/ml
Limitations This Plakophilin 2 antibody is available for research use only.
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Description

Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. PKP2 is a constituent of the desmosomal plaque in simple epithelia, some stratified epithelia, and some nonepithelial cells. It is also enriched in the karyoplasm of cells of various types, including those lacking desmosomes. PKP proteins participate in linking cadherins to intermediate filaments in the cytoskeleton and this gene product may regulate the signaling activity of beta-catenin. Plakophilin-2 has been shown to interact with Desmoplakin, Plakoglobin and Desmoglein 1.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Plakophilin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human PKP2 (KKTDFVNSRTAKAYHSLKD) was used as the immunogen for this Plakophilin 2 antibody (100% mouse homology).

Storage

After reconstitution, the Plakophilin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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