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Home >> Antibodies >> INDOL1 Antibody

INDOL1 Antibody (R30692)

  Catalog No Formulation Size Price (USD)  
Image R30692 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of INDOL1 antibody and Lane 1: A549; 2: human placenta; 3: A431 cell lysate. Expected molecular weight: ~47kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q6ZQW0
Applications Western blot : 0.5-1ug/ml
Limitations This INDOL1 antibody is available for research use only.
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Description

IDO2 (Indoleamine 2,3-dioxygenase 2), also called Indoleamine 2,3-dioxygenase-like 1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the INDOL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Amino acids 1-20 (MLHFHYYDTSNKIMEPHRPN-human) were used as the immunogen for this INDOL1 antibody.

Storage

After reconstitution, the INDOL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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