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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Titration of the ICAM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 191-218 from the human protein was used as the immunogen for this ICAM2 antibody.
Aliquot the ICAM2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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