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Home >> Antibodies >> CCR7 Antibody

CCR7 Antibody (F48967)

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  Catalog No Formulation Size Price (USD)  
Image F48967-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F48967-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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CCR7 antibody western blot analysis in 293 (lane 1), Ramos (2), MDA-MB231 (3) cell line and mouse spleen tissue (4) lysate. Predicted size ~45 kDa
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CCR7 antibody western blot analysis in 293 (lane 1), Ramos (2), MDA-MB231 (3) cell line and mouse spleen tissue (4) lysate. Predicted size ~45 kDa
CCR7 antibody IHC analysis in formalin fixed and paraffin embedded human tonsil.
Confocal immunofluorescent analysis of CCR7 antibody with MDA-MB231 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
CCR7 antibody flow cytometric analysis of 293 cells (right histogram) compared to a negative control (left histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P32248
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Immunofluorescence : 1:10-1:50
Flow Cytometry : 1:10-1:50
Limitations This CCR7 antibody is available for research use only.
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Description

CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.

Application Notes

Titration of the CCR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 11-37 from the human protein was used as the immunogen for this CCR7 antibody.

Storage

Aliquot the CCR7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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