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Home >> Antibodies >> CAMKK2 Antibody

CAMKK2 Antibody (F50127)

  Catalog No Formulation Size Price (USD)  
Image F50127-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F50127-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC analysis of FFPE human brain tissue stained with CAMKK2 antibody
Western blot analysis of CAMKK2 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the CAMKK2 gene (2). Predicted molecular weight 60-65 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q96RR4
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50
Limitations This CAMKK2 antibody is available for research use only.
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Description

CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.

Application Notes

Titration of the CAMKK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 483-512 from the human protein was used as the immunogen for this CAMKK2 antibody.

Storage

Aliquot the CAMKK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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