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- Tel: 858.663.9055
- Email: info@nsjbio.com
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On ligand binding, BMPR1A forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. Positively regulates chondrocyte differentiation through GDF5 interaction (By similarity). [UniProt]
Titration of the BMPR1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1-30 from the human protein was used as the immunogen for this BMPR1A antibody.
Aliquot the BMPR1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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