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Home >> Antibodies >> BMP6 Antibody

BMP6 Antibody (F45401)

  Catalog No Formulation Size Price (USD)  
Image F45401-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F45401-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC analysis of FFPE human lung carcinoma tissue stained with BMP6 antibody
Western blot testing of BMP6 antibody and HL-60 cell lysate. Expected molecular weight: ~57kDa (precursor), ~46kDa (cleaved precursor), 18-23kDa (mature).
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P22004
Localization Cytoplasmic
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This BMP6 antibody is available for research use only.
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Description

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, Bmp6 has a proposed role in early development. In addition, the fact that BMP6 is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Application Notes

Titration of the BMP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 25-55 from the human protein was used as the immunogen for this BMP6 antibody.

Storage

Aliquot the BMP6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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