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Home >> Antibodies >> ZWINT Antibody

ZWINT Antibody (R32455)

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  Catalog No Formulation Size Price (USD)  
Image R32455 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of rat skeletal muscle lysate with ZWINT antibody at 0.5ug/ml. Expected molecular weight ~31 kDa.
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Western blot testing of rat skeletal muscle lysate with ZWINT antibody at 0.5ug/ml. Expected molecular weight ~31 kDa.
IHC testing of FFPE mouse brain with ZWINT antibody at 1ug/ml. HIER: steam in pH6 citrate buffer and allow to cool prior to staining.
IHC testing of FFPE rat brain with ZWINT antibody at 1ug/ml. HIER: steam in pH6 citrate buffer and allow to cool prior to staining.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt O95229
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 1-2ug/ml
Limitations This ZWINT antibody is available for research use only.
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Description

ZW10 interactor (Zwint-1) is a protein that in humans is encoded by the ZWINT gene. This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Application Notes

Optimal dilution of the ZWINT antibody should be determined by the researcher.

Immunogen

Amino acids Q29-Q249 from the human protein were used as the immunogen for the ZWINT antibody.

Storage

Prior to reconstitution, store at 4oC. After reconstitution, the ZWINT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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