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- Email: info@nsjbio.com
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF622 (zinc-finger protein 622), also known as ZPR9 (zinc-fingerlike protein 9), is a 477 amino acid protein that localizes to both the nucleus and the cytoplasm. Expressed in liver, spleen, lung, kidney and brain, ZNF622 is thought to activate the bound transcription factor B-Myb and, through this activation, may play a role in embryonic development. ZNF622 contains two U1-type zinc fingers and exists as either a homodimer or a heterodimer that can be phosphorylated by MELK (maternal embryonic leucine zipper kinase). Overexpression of ZNF266 may be associated with liver metastases, carcinomatoses and colorectal carcinomas.
Optimal dilution of the ZNF622 antibody should be determined by the researcher.
Recombinant full-length human ZNF622 protein was used as the immunogen for the ZNF622 antibody.
Aliquot the ZNF622 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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