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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Zinc fingers and homeoboxes protein 3 (ZHX3) is a nuclear regulatory protein involved in transcriptional control, differentiation-associated gene expression, and developmental signaling pathways. ZHX3 Antibody / Transcriptional Regulation Marker is suitable for studies involving nuclear transcription-associated proteins, developmental regulatory networks, and zinc finger homeobox family signaling pathways. ZHX3 belongs to the ZHX family of transcription-associated regulatory proteins characterized by zinc finger motifs and homeobox domains that contribute to coordinated control of gene expression and cellular differentiation programs.
ZHX3 antibody, also referred to as Zinc fingers and homeoboxes 3 antibody, Zinc finger homeobox protein antibody, and ZHX family transcription factor antibody in the literature, recognizes a nuclear-associated regulatory protein implicated in transcriptional repression and modulation of differentiation-associated signaling pathways. Members of the ZHX protein family frequently function within multiprotein transcriptional complexes that regulate developmental gene expression, lineage specification, and adaptive cellular responses. Through interactions with DNA-associated regulatory machinery, ZHX3 contributes to coordinated transcriptional regulation within multiple tissue and cellular contexts.
ZHX family proteins are broadly associated with pathways controlling proliferation, differentiation, tissue homeostasis, and developmental signaling. The presence of zinc finger motifs and homeobox domains allows these proteins to participate in transcription-associated regulatory networks linked to chromatin organization and nuclear signaling pathways. ZHX3 is primarily localized within the nucleus, consistent with its role as a transcription-associated regulatory protein involved in gene expression control and cellular identity maintenance.
Altered expression of transcriptional regulatory proteins such as ZHX3 may contribute to dysregulated differentiation, abnormal cellular signaling, and disease-associated transcriptional remodeling. ZHX family proteins have been investigated in developmental biology, epithelial differentiation pathways, and tumor-associated transcriptional regulation. Because transcriptional control proteins coordinate broad gene expression programs, ZHX3 remains relevant for investigations involving nuclear regulatory mechanisms, developmental signaling pathways, and differentiation-associated cellular processes.
Immunohistochemistry, immunofluorescence, and flow cytometry analyses support detection of endogenous ZHX3 expression across multiple research applications. HuProt(TM) protein microarray specificity validation with clone PCRP-ZHX3-1G3 further demonstrates highly selective recognition of ZHX3 among more than 19,000 full-length human proteins. The combined validation profile supports use of this mouse monoclonal antibody for investigations involving transcriptional regulation, zinc finger homeobox proteins, nuclear signaling pathways, and differentiation-associated gene expression programs.
An antibody targeting ZHX3 can therefore support studies involving transcriptional regulatory complexes, nuclear differentiation pathways, developmental signaling networks, chromatin-associated gene expression control, and zinc finger homeobox family biology.
ZHX3 functions in nuclear transcriptional regulation and differentiation-associated signaling pathways; explore related regulatory proteins and cellular pathway targets on our Cell Biology Antibodies landing page.
Optimal dilution of the ZHX3 Antibody / Transcriptional Regulation Marker should be determined by the researcher.
Recombinant full-length human ZHX3 protein was used as the immunogen for the ZHX3 antibody.
Aliquot the ZHX3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
ZHX3 antibody, Zinc fingers and homeoboxes 3 antibody, Zinc finger homeobox protein antibody, ZHX family transcription factor antibody, Nuclear transcriptional regulator antibody
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