- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ZFP90 Antibody / Zinc Finger Protein 90 Microarray Specificity Validated Antibody [clone PCRP-ZFP90-1C5] (V4433)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V4433-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
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V4433-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
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V4433SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2a |
| Clone Name | PCRP-ZFP90-1C5 |
| Purity | Protein A/G affinity |
| UniProt | Q8TF47 |
| Localization | Nucleus |
| Applications | Flow Cytometry : 1-2ug/million cells |
| Limitations | This ZFP90 Antibody / Zinc Finger Protein 90 Microarray Specificity Validated Antibody is available for research use only. |
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Zinc finger protein 90 (ZFP90), also known as ZNF756, is a nuclear transcription-associated protein belonging to the C2H2-type zinc finger protein family, a large group of DNA-binding proteins involved in transcriptional regulation and chromatin organization. ZFP90 Antibody / Zinc Finger Protein 90 Microarray Specificity Validated Antibody (clone PCRP-ZFP90-1C5) is designed as a reference reagent for detecting ZFP90 with high specificity across complex biological samples. ZFP90 antibody, also referred to as Zinc finger protein 90 antibody in the literature, is widely used in studies of gene regulation, transcription factor networks, and epigenetic control.
ZFP90 contains multiple zinc finger domains that facilitate sequence-specific DNA binding, enabling it to function as a regulator of transcription. Proteins in this class often act as transcriptional repressors or activators depending on their interacting partners and cellular context. ZFP90 is thought to participate in chromatin-associated processes, potentially influencing gene expression through interactions with co-regulatory complexes and DNA regulatory elements.
Members of the zinc finger protein family are frequently involved in developmental processes, cell differentiation, and maintenance of cellular identity. While the specific functional roles of ZFP90 are still being defined, its structural features suggest involvement in transcriptional modulation and genome regulation. Expression of ZFP90 has been observed in a range of tissues, with nuclear localization consistent with its role in gene regulatory mechanisms.
In immunohistochemistry and immunofluorescence applications, ZFP90 is expected to exhibit predominantly nuclear staining, reflecting its function as a transcription-associated protein. Western blot analysis typically detects ZFP90 at a molecular weight consistent with its predicted size based on amino acid sequence, supporting its identification in biochemical assays.
A defining feature of this antibody is its validation using protein microarray analysis across more than 19,000 full-length human proteins, demonstrating highly selective binding to ZFP90 with minimal off-target interaction. The Z-score reflects the strength of binding signal relative to the array background, while the S-score represents the separation between the top-ranked target and the next highest signal, confirming target specificity in a proteome-wide context.
The mouse monoclonal clone PCRP-ZFP90-1C5 antibody provides reliable and specific detection of ZFP90 in research applications. Its combination of structural target recognition and microarray-confirmed specificity makes it well suited for studies of transcriptional regulation, chromatin biology, and gene expression analysis.
This antibody is part of a collection of Human Protein Microarray validated antibodies that have been screened for specificity across thousands of proteins.
Optimal dilution of the ZFP90 Antibody / Zinc Finger Protein 90 Microarray Specificity Validated Antibody should be determined by the researcher.
A recombinant fragment corresponding to the protein domain of ZFP90 was used as the immunogen for the ZFP90 antibody.
Aliquot the ZFP90 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
ZFP90 antibody, Zinc finger protein 90 antibody, ZNF756 antibody, Zinc finger transcription factor antibody, KRAB zinc finger protein antibody
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