Zebrafish PDGFRA Antibody / PDGFR Alpha Antibody (RZ1404)

Zebrafish PDGFRA Antibody Spinal Cord IHC. Immunohistochemistry staining of paraffin-embedded zebrafish spinal cord tissue using Zebrafish PDGFRA Antibody / PDGFR Alpha Antibody demonstrates membranous and cytoplasmic HRP-DAB brown staining within spinal cord-associated cellular populations. The staining pattern is consistent with expression of PDGFRA, a receptor tyrosine kinase that mediates platelet-derived growth factor signaling and regulates cellular proliferation, migration, survival, and differentiation during vertebrate development. PDGFRA plays important roles in neural crest biology, mesenchymal tissue development, and organization of the developing nervous system. HIER was performed using EDTA buffer prior to staining. Tissue sections were blocked with 10% goat serum and incubated with primary antibody at 2 ug/ml overnight at 4C before detection with peroxidase-conjugated goat anti-rabbit IgG and DAB chromogen.

Zebrafish PDGFRA Antibody Brain IHC. Immunohistochemistry staining of paraffin-embedded zebrafish brain tissue using Zebrafish PDGFRA Antibody / PDGFR Alpha Antibody demonstrates widespread HRP-DAB brown staining within brain-associated cellular and stromal structures. The staining pattern is consistent with expression of PDGFRA, a receptor tyrosine kinase that mediates platelet-derived growth factor signaling and regulates cellular proliferation, migration, differentiation, and survival during vertebrate development. PDGFRA plays important roles in neural development, neural crest-derived cell biology, tissue morphogenesis, and growth factor-mediated signaling pathways that contribute to organization of the developing nervous system. HIER was performed using EDTA buffer prior to staining. Tissue sections were blocked with 10% goat serum and incubated with primary antibody at 2 ug/ml overnight at 4C before detection with peroxidase-conjugated goat anti-rabbit IgG and DAB chromogen.