- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Zebrafish Nol10 Antibody / Nucleolar protein 10 (RZ1140)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RZ1140 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 539 |
| Availability | 2-3 weeks |
| Species Reactivity | Zebrafish |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity chromatography |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| UniProt | Q802W4 |
| Localization | Nuclear |
| Applications | Immunohistochemistry (FFPE) : 2-5 ug/ml |
| Limitations | This Zebrafish Nol10 antibody is available for research use only. |
|
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By immunoprecipitation of human AATF it was discovered that AATF forms a salt-stable protein complex together with neuroguidin (NGDN) and NOL10 and demonstrated that the AATF-NGDN-NOL10 (ANN) complex functions in ribosome biogenesis. All three ANN complex members localize to nucleoli and display a mutual dependence with respect to protein stability. Mapping of protein-protein interaction domains revealed the importance of both the evolutionary conserved WD40 repeats in NOL10 and the UTP3/SAS10 domain in NGDN for complex formation.
Optimal dilution of the Zebrafish Nol10 antibody should be determined by the researcher.
An E.coli-derived zebrafish Nol10 recombinant protein (amino acids Y73-D497) was used as the immunogen for the Zebrafish Nol10 antibody.
After reconstitution, the Zebrafish Nol10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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