- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Zebrafish LPL Antibody / Lipoprotein Lipase Antibody (RZ1381)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RZ1381 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 539 |
|
| Species Reactivity | Zebrafish |
| Format | Antigen affinity purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Buffer | Lyophilized from a buffered saline solution containing 2% trehalose. Reconstitute with 0.2 mL distilled water to yield a final antibody concentration of 500 ug/mL. |
| UniProt | Q6P2U2 |
| Applications | Western Blot : 0.5-1ug/ml |
| Limitations | This Zebrafish LPL Antibody / Lipoprotein Lipase Antibody is available for research use only. |
|
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Zebrafish LPL Antibody / Lipoprotein Lipase Antibody is useful for studying Lipoprotein Lipase (LPL), a key enzyme involved in lipid metabolism and energy homeostasis. In zebrafish, Lipoprotein Lipase is encoded by the LPLA gene and functions in the hydrolysis of triglycerides contained within circulating lipoproteins, releasing free fatty acids that can be taken up and utilized by tissues for energy production, membrane synthesis, and lipid storage. Through this activity, LPL serves as a central regulator of lipid utilization and nutrient distribution throughout the organism.
Lipoprotein Lipase is essential for maintaining normal lipid balance because it controls the availability of fatty acids derived from triglyceride-rich lipoproteins. By regulating lipid uptake and utilization, LPL influences cellular metabolism, energy production, tissue growth, and developmental processes. The enzyme is particularly important in metabolically active tissues that depend on a continuous supply of fatty acids to support physiologic function and cellular homeostasis.
In zebrafish, LPL contributes to pathways involved in embryonic growth, tissue maturation, nutrient utilization, and lipid transport. Because zebrafish embryos develop externally and are highly amenable to genetic manipulation and imaging, they have become valuable models for investigating lipid metabolism and energy regulation during vertebrate development. Analysis of LPL expression can provide insight into mechanisms that govern lipid handling, metabolic adaptation, and nutrient-responsive signaling pathways.
Beyond its role in triglyceride hydrolysis, LPL participates in broader metabolic networks that influence energy balance, lipid storage, and fatty acid utilization. Proper regulation of lipid metabolism is required for normal development, tissue maintenance, and physiologic adaptation. Consequently, Lipoprotein Lipase is frequently studied in developmental biology, cardiovascular research, metabolic regulation, obesity-associated pathways, and investigations of lipid-related disease mechanisms.
Zebrafish has emerged as a powerful model for examining genes involved in lipid metabolism because many pathways regulating lipoprotein processing and fatty acid utilization are highly conserved among vertebrates. LPL expression is therefore commonly evaluated in studies of cardiovascular physiology, metabolic homeostasis, nutrient transport, developmental biology, and lipid-associated signaling networks. These characteristics make Lipoprotein Lipase an important target for understanding how organisms regulate energy availability and lipid utilization.
Zebrafish LPL antibodies are commonly used in immunohistochemistry, immunofluorescence, western blotting, and related protein detection applications to evaluate Lipoprotein Lipase expression and localization. These reagents support investigations of lipid metabolism, triglyceride processing, fatty acid utilization, developmental biology, cardiovascular physiology, and metabolic regulation in zebrafish research models.
Learn more about Lipoprotein Lipase function in lipid metabolism, triglyceride hydrolysis, fatty acid utilization, and metabolic regulation on our LPL Antibody page.
This Zebrafish antibody is part of a broader Zebrafish / Danio rerio antibody panel offered by NSJ Bioreagents.
The optimal working dilution of the Zebrafish LPL Antibody / Lipoprotein Lipase Antibody should be determined empirically by the investigator.
An E.coli-derived Zebrafish LPLA recombinant protein (amino acids D52-E511) was used as the immunogen for the Zebrafish LPL / LPLA Antibody.
After reconstitution, the Zebrafish LPL / LPLA Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Zebrafish Lipoprotein Lipase Antibody, Zebrafish LPLA Antibody, Zebrafish Triglyceride Lipase Antibody, Zebrafish Lipid Metabolism Enzyme Antibody, Zebrafish Fatty Acid Mobilization Protein Antibody, Zebrafish Lipid Uptake Regulator Antibody
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