Zebrafish HSD17B1 Antibody / 17B-HSD1 Antibody (RZ1354)

Zebrafish HSD17B1 / 17B-HSD1 Antibody Brain IHC. Immunohistochemistry staining of FFPE zebrafish brain tissue using Zebrafish HSD17B1 Antibody demonstrates cytoplasmic HRP-DAB brown staining within scattered neural-associated cellular populations throughout brain tissue. The staining pattern is consistent with expression of Hydroxysteroid 17-Beta Dehydrogenase 1 (HSD17B1), also known as 17B-HSD1, an enzyme that catalyzes key reactions in estrogen biosynthesis and steroid hormone metabolism. Signal is observed within brain-associated tissue compartments, reflecting the established role of steroidogenic enzymes in neuroendocrine regulation, hormone-responsive signaling pathways, and maintenance of vertebrate nervous system function. Heat mediated antigen retrieval was performed in EDTA buffer. Primary antibody was incubated overnight at 4°C followed by detection using a peroxidase-conjugated goat anti-rabbit secondary antibody and DAB chromogen.

Zebrafish HSD17B1 / 17B-HSD1 Antibody Ovary IHC. Immunohistochemistry staining of FFPE zebrafish ovary tissue using Zebrafish HSD17B1 Antibody demonstrates strong cytoplasmic HRP-DAB brown staining within ovarian follicular and oocyte-associated cellular populations. The staining pattern is consistent with expression of Hydroxysteroid 17-Beta Dehydrogenase 1 (HSD17B1), also known as 17B-HSD1, a key steroidogenic enzyme that catalyzes the conversion of estrone to biologically active estradiol. Prominent staining within ovarian tissue is consistent with the established role of HSD17B1 in estrogen biosynthesis, reproductive physiology, gonadal development, and endocrine regulation. Heat mediated antigen retrieval was performed in EDTA buffer. Primary antibody was incubated overnight at 4°C followed by detection using a peroxidase-conjugated goat anti-rabbit secondary antibody and DAB chromogen.