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Home >> Antibodies >> Zebrafish Grin1 Antibody / Grin1a / Grin1b / Nmdar1.1

Zebrafish Grin1 Antibody / Grin1a / Grin1b / Nmdar1.1 (RZ1173)

  Catalog No Formulation Size Price (USD)  
Image RZ1173 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 539
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Immunohistochemical analysis of Grin1a/b protein using Zebrafish Grin1 antibody and paraffin-embedded zebrafish brain tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Availability 2-3 weeks
Species Reactivity Zebrafish
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity chromatography
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt F1R366
Localization Cell membrane
Applications Immunohistochemistry (FFPE) : 2-5 ug/ml
Limitations This Zebrafish Grin1 antibody is available for research use only.
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Description

Glutamate [NMDA] receptor subunit zeta-1 is a protein that in humans is encoded by the GRIN1 gene. The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Application Notes

Optimal dilution of the Zebrafish Grin1 antibody should be determined by the researcher.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of zebrafish Grin1a/b was used as the immunogen for the Zebrafish Grin1 antibody. This antibody will detect isoforms a & b.

Storage

After reconstitution, the Zebrafish Grin1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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