Zebrafish Gata4 Antibody / GATA-binding factor 4 (RZ1186)

Description

GATA-binding factor 4 (Gata4) is a zinc finger transcription factor belonging to the GATA family, which regulates gene expression during embryonic development and cell differentiation. In zebrafish (Danio rerio), Gata4 plays a critical role in the development of the heart, endoderm, and gastrointestinal tract, mirroring its conserved function in vertebrate organogenesis.

Gata4 is expressed early during zebrafish embryogenesis, particularly in the cardiac mesoderm and endodermal precursors. It functions as a key regulator of cardiomyocyte differentiation, heart tube formation, and gut development. Gata4 also interacts with other transcription factors such as Nkx2.5 and Tbx5 to coordinate cardiac gene expression programs.

Due to its essential role in heart development and its evolutionary conservation, zebrafish Gata4 is widely studied in models of congenital heart disease, organ specification, and regenerative biology. It serves as a valuable molecular marker and research target for developmental biology, gene regulation, and disease modeling.

Application Notes

Optimal dilution of the Zebrafish Gata4 antibody should be determined by the researcher.

Immunogen

E. coli-derived zebrafish Gata4 recombinant protein (amino acids M1-M332) was used as the immunogen for the Zebrafish Gata4 antibody.

Storage

After reconstitution, the Zebrafish Gata4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.