- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Zebrafish CTGF Antibody / CCN2A Antibody recognizes Cellular Communication Network Factor 2A (CCN2A), also known as Connective Tissue Growth Factor (CTGF), a secreted matricellular protein that regulates extracellular matrix organization, tissue remodeling, cellular differentiation, and developmental signaling. CCN2A belongs to the CCN family of extracellular regulatory proteins and functions as an important mediator of communication between cells and their surrounding microenvironment. In zebrafish, CCN2A contributes to tissue growth, connective tissue formation, and developmental processes that require coordinated regulation of extracellular matrix deposition and cellular behavior.
CCN family proteins interact with growth factors, integrins, extracellular matrix components, and cell surface receptors to influence numerous biological pathways. Through these interactions, CCN2A helps regulate cell adhesion, migration, proliferation, and differentiation. Rather than acting as a traditional growth factor, CCN2A functions as a signaling modulator that integrates extracellular cues and helps coordinate tissue-specific developmental responses. This role makes CCN2A particularly important in tissues undergoing active remodeling, growth, and morphogenesis.
Zebrafish provide an excellent model for studying connective tissue biology, skeletal development, cardiovascular development, and regenerative processes. Expression of CCN2A has been associated with tissues involved in extracellular matrix production and structural organization, making it a valuable marker for investigations of organogenesis and tissue maturation. Researchers frequently examine CCN2A during formation of cartilage, bone, vasculature, and other connective tissue-rich structures where extracellular matrix signaling plays a critical role in normal development.
Beyond embryonic development, CCN2A is relevant to studies of wound healing, tissue repair, fibrosis, and regeneration. The remarkable regenerative capacity of zebrafish has made CCN2A an important target for understanding how extracellular signaling networks regulate tissue restoration following injury. Alterations in CCN2A expression can influence matrix deposition, cellular recruitment, and structural remodeling, providing insight into mechanisms that control tissue regeneration and homeostasis.
At NSJ Bioreagents, we provide highly validated antibodies for developmental biology, extracellular matrix research, and zebrafish model systems. Zebrafish CTGF Antibody / CCN2A Antibody is useful for investigations of connective tissue development, extracellular matrix regulation, tissue remodeling, regenerative biology, and organogenesis. Continued study of CCN2A is expanding our understanding of how extracellular signaling pathways coordinate vertebrate development, tissue repair, and structural homeostasis.
Researchers studying connective tissue growth factor signaling, extracellular matrix regulation, fibrosis, and tissue remodeling may also be interested in our CTGF Antibody page.
This Zebrafish antibody is part of a broader Zebrafish / Danio rerio antibody panel offered by NSJ Bioreagents.
The optimal working dilution of the Zebrafish CTGF Antibody / CCN2A Antibody should be determined empirically by the investigator.
An E.coli-derived Zebrafish Connective Tissue Growth Factor recombinant protein (amino acids A57-A345) was used as the immunogen for the Zebrafish CTGF / CCN2A Antibody.
After reconstitution, the Zebrafish CTGF / CCN2A Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Zebrafish CCN2A Antibody, Zebrafish CTGF Antibody, Zebrafish Connective Tissue Growth Factor Antibody, Zebrafish CCN Family Protein 2A Antibody, Zebrafish Cellular Communication Network Factor 2A Antibody, Zebrafish Fibrogenic Growth Factor Antibody
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