- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Zebrafish Beta Tubulin 1 Antibody / TUBB1 Antibody (RZ1350)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RZ1350 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 539 |
|
| Species Reactivity | Zebrafish |
| Format | Antigen affinity purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Buffer | Lyophilized from a buffered saline solution containing 2% trehalose. Reconstitute with 0.2 mL distilled water to yield a final antibody concentration of 500 ug/ml. |
| UniProt | E7FC32 |
| Applications | Western Blot : 0.5-1ug/ml |
| Limitations | This Zebrafish Beta Tubulin 1 Antibody / TUBB1 Antibody is available for research use only. |
|
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Zebrafish Beta Tubulin 1 Antibody / TUBB1 Antibody recognizes Tubulin Beta 1 (TUBB1), a member of the beta-tubulin protein family that serves as a structural component of microtubules. Microtubules are dynamic cytoskeletal polymers that contribute to cell shape, intracellular transport, chromosome segregation, motility, and tissue organization. Through assembly with alpha-tubulin subunits, TUBB1 participates in formation of the microtubule network that supports essential cellular processes throughout development and adult physiology. The highly conserved nature of tubulin proteins has established zebrafish as an important vertebrate model for investigating cytoskeletal organization and microtubule-dependent biological functions.
Microtubules play critical roles during embryonic development by regulating cell division, migration, differentiation, and morphogenesis. In zebrafish, TUBB1 expression contributes to the cytoskeletal framework required for tissue organization and cellular architecture. Proper microtubule assembly is essential for nervous system development, organ formation, intracellular trafficking, and maintenance of cellular polarity. Consequently, TUBB1 and related tubulin family members are frequently examined in studies investigating developmental biology, cell structure, and cytoskeletal dynamics.
The tubulin cytoskeleton also participates in intracellular transport processes through interactions with molecular motor proteins including kinesins and dyneins. These transport systems facilitate movement of vesicles, organelles, signaling molecules, and protein complexes throughout the cell. Because microtubule organization influences numerous aspects of cellular function, alterations in tubulin expression or microtubule dynamics can affect development, tissue homeostasis, and physiological regulation. Researchers commonly evaluate tubulin proteins as markers of cytoskeletal integrity and cellular organization.
Zebrafish provide unique advantages for examining cytoskeletal biology because developmental processes can be directly visualized in living embryos and larvae. Expression studies involving TUBB1 may provide insight into tissue-specific microtubule organization, cellular differentiation, and developmental regulation. Because microtubule networks are fundamental to nearly every aspect of vertebrate cell biology, TUBB1 remains a valuable target for studies focused on cytoskeletal structure and function.
At NSJ Bioreagents, we provide highly validated antibodies for cell biology, developmental biology, and zebrafish research. Zebrafish Beta Tubulin 1 Antibody / TUBB1 Antibody targets a key component of the microtubule cytoskeleton. TUBB1 expression is studied in the context of cellular architecture, microtubule organization, intracellular transport, tissue development, and cytoskeletal regulation. Continued investigation of TUBB1 is expanding our understanding of the molecular mechanisms that govern cell structure, developmental processes, and vertebrate physiology.
This Zebrafish antibody is part of a broader Zebrafish / Danio rerio antibody panel offered by NSJ Bioreagents.
The optimal working dilution of the Zebrafish Beta Tubulin 1 Antibody / TUBB1 Antibody should be determined empirically by the investigator.
An E.coli-derived Zebrafish beta I Tubulin/TUBB1 recombinant protein (amino acids M1-D427) was used as the immunogen for the Zebrafish Beta Tubulin 1 / TUBB1 Antibody.
After reconstitution, the Zebrafish Beta Tubulin 1 / TUBB1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Zebrafish TUBB1 Antibody, Zebrafish Tubulin Beta 1 Antibody, Zebrafish Beta-Tubulin 1 Antibody, Zebrafish Microtubule Protein Antibody, Zebrafish Cytoskeletal Tubulin Antibody, Zebrafish Platelet Tubulin Antibody
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