- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Zebrafish ALDH1A3 Antibody / Retinoic Acid Biosynthesis Enzyme Antibody is designed for the detection and study of ALDH1A3, the zebrafish ortholog of human Aldehyde Dehydrogenase 1 Family Member A3. ALDH1A3 is an NAD-dependent oxidoreductase that catalyzes the conversion of retinaldehyde to retinoic acid, a critical signaling molecule involved in vertebrate development and tissue patterning. Through its role in retinoid metabolism, ALDH1A3 contributes to cellular differentiation, organogenesis, and maintenance of developmental signaling pathways.
ALDH1A3 belongs to the aldehyde dehydrogenase superfamily, a group of enzymes responsible for oxidation of aldehydes to their corresponding carboxylic acids. Among these enzymes, ALDH1A3 is particularly important for the synthesis of retinoic acid, which functions as a morphogen regulating transcriptional programs that control embryonic patterning and tissue specification. Because retinoic acid signaling is highly conserved among vertebrates, ALDH1A3 has become an important target in developmental biology research.
Zebrafish provide a valuable model for studying retinoid signaling because developmental processes and metabolic pathways are strongly conserved between fish and mammals. Investigations utilizing Zebrafish ALDH1A3 Antibody can help characterize expression patterns associated with embryogenesis, nervous system development, sensory organ formation, and tissue differentiation. Studies of ALDH1A3 continue to provide important insights into the mechanisms that coordinate vertebrate development and cellular specialization.
Beyond developmental biology, ALDH1A3 has attracted considerable interest in stem cell biology, regenerative medicine, and cancer research. Retinoic acid signaling pathways influence cellular identity, differentiation status, and tissue homeostasis, making ALDH1A3 a useful marker for studies examining developmental metabolism and signaling networks. Researchers utilize Zebrafish ALDH1A3 Antibody to investigate retinoid metabolism, developmental regulation, and molecular mechanisms governing vertebrate physiology.
Learn more about ALDH1A3 function, retinoic acid synthesis, and retinoid metabolism on our ALDH1A3 Antibody / Retinoic Acid Synthesis Enzyme page.
This Zebrafish antibody is part of a broader Zebrafish / Danio rerio antibody panel offered by NSJ Bioreagents.
The optimal working dilution of the Zebrafish ALDH1A3 Antibody / RALDH3 Antibody should be determined empirically by the investigator.
An E.coli-derived Zebrafish ALDH1A3 recombinant protein (amino acids M1-L513) was used as the immunogen for the Zebrafish ALDH1A3 Antibody.
After reconstitution, the Zebrafish ALDH1A3 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Zebrafish ALDH1A3 Antibody, Zebrafish Aldehyde Dehydrogenase 1 Family Member A3 Antibody, Zebrafish Retinaldehyde Dehydrogenase 3 Antibody, Zebrafish RALDH3 Antibody, Zebrafish Retinoic Acid Biosynthesis Enzyme Antibody, Zebrafish Aldehyde Oxidoreductase Antibody, Zebrafish Developmental Metabolism Protein Antibody
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