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Home >> Antibodies >> Zebrafish Afg3l2 Antibody / AFG3 like protein 2

Zebrafish Afg3l2 Antibody / AFG3 like protein 2 (RZ1127)

  Catalog No Formulation Size Price (USD)  
Image RZ1127 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 539
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Western blot analysis of Zebrafish Afg3l2 protein using Zebrafish Afg3l2 antibody and 1) zebrafish head and 2) zebrafish embryo tissue lysate. Predicted molecular weight ~89 kDa.
Availability 2-3 weeks
Species Reactivity Zebrafish
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity chromatography
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt A9JRG9
Applications Western Blot : 0.5-1 ug/ml
Limitations This Zebrafish Afg3l2 antibody is available for research use only.
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Description

AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. In humans, it is encoded by the AFG3L2 gene. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome.

Application Notes

Optimal dilution of the Zebrafish Afg3l2 antibody should be determined by the researcher.

Immunogen

An E.coli-derived zebrafish Afg3l2 recombinant protein (amino acids G161-D245) was used as the immunogen for the Zebrafish Afg3l2 antibody.

Storage

After reconstitution, the Zebrafish Afg3l2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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