Zebrafish ACVR1L Antibody / ALK8 Antibody (RZ1360)

Zebrafish ACVR1L / ALK8 Antibody Brain IHC. Immunohistochemistry staining of FFPE zebrafish brain tissue using Zebrafish ACVR1L Antibody demonstrates widespread cytoplasmic HRP-DAB brown staining throughout neural tissue regions, with prominent immunoreactivity observed in densely cellular brain-associated structures. The staining pattern is consistent with expression of Activin Receptor Type 1-Like (ACVR1L), also known as ALK8, a serine/threonine kinase receptor that mediates BMP and TGF-beta signaling during vertebrate development. Expression within neural tissues is consistent with the established role of ACVR1L in embryonic patterning, neural development, cellular differentiation, and regulation of developmental signaling pathways. Heat mediated antigen retrieval was performed in EDTA buffer. Primary antibody was incubated overnight at 4°C followed by detection using a peroxidase-conjugated goat anti-rabbit secondary antibody and DAB chromogen.

Zebrafish ACVR1L / ALK8 Antibody Liver IHC. Immunohistochemistry staining of FFPE zebrafish liver tissue using Zebrafish ACVR1L Antibody demonstrates widespread cytoplasmic HRP-DAB brown staining throughout hepatocyte populations. The staining pattern is consistent with expression of Activin Receptor Type 1-Like (ACVR1L), also known as ALK8, a transmembrane serine/threonine kinase receptor that mediates BMP and TGF-beta signaling pathways. Hepatic expression of ACVR1L is consistent with the broad involvement of BMP receptor signaling in cellular differentiation, tissue homeostasis, developmental regulation, and growth factor-mediated signaling processes. Heat mediated antigen retrieval was performed in EDTA buffer. Primary antibody was incubated overnight at 4°C followed by detection using a peroxidase-conjugated goat anti-rabbit secondary antibody and DAB chromogen.