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Home >> Antibodies >> Zbp1 Antibody / Z-DNA-binding protein 1 / Dai

Zbp1 Antibody / Z-DNA-binding protein 1 / Dai (RQ6581)

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  Catalog No Formulation Size Price (USD)  
Image RQ6581 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Immunofluorescent staining of FFPE mouse RM-1 cells with Zbp1 antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
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Immunofluorescent staining of FFPE mouse RM-1 cells with Zbp1 antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of 1) rat liver, 2) mouse kidney, 3) mouse HEPA1-6, 4) rat thymus and 5) mouse thymus tissue lysate with Zbp1 antibody. Predicted molecular weight: 15-49 kDa (multiple isoforms) but can be observed at up to ~60 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q9QY24
Localization Cytoplasmic, nuclear
Applications Western blot : 1-2ug/ml
Immunofluorescence (FFPE) : 5ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This Zbp1 antibody is available for research use only.
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Description

Z-DNA-binding protein 1, also known as DNA-dependent activator of IFN-regulatory factors (DAI) and DLM-1, is a protein that in humans is encoded by the ZBP1 gene. This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Application Notes

Optimal dilution of the Zbp1 antibody should be determined by the researcher.

Immunogen

Recombinant mouse protein (amino acids A2-D382) was used as the immunogen for the Zbp1 antibody.

Storage

After reconstitution, the Zbp1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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