- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
XRCC5 Antibody for IF / Ku80 Immunofluorescence Antibody (F41815)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
F41815-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 439 | |
|
|
F41815-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 205 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P13010 |
| Applications | Western Blot : 1:1000 Immunofluorescence : 1:10-1:50 Flow Cytometry : 1:10-1:50 |
| Limitations | This XRCC5 antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
X-ray repair cross-complementing protein 5 (XRCC5), also known as Ku80, is a DNA repair factor that plays a central role in non-homologous end joining and is widely used as a marker for nuclear DNA damage response pathways. XRCC5 Antibody for IF is specifically suited for immunofluorescence applications that require high-resolution visualization of protein localization within cells, enabling researchers to examine the spatial distribution of XRCC5 across nuclear and cytoplasmic compartments. As part of the Ku heterodimer with XRCC6, XRCC5 binds DNA double-strand breaks and coordinates recruitment of repair machinery, making its localization patterns highly relevant to cellular stress and genome integrity.
XRCC5 antibody, also referred to as Ku80 antibody, is particularly valuable in immunofluorescence imaging where subcellular distribution provides critical biological insight. XRCC5 is predominantly nuclear under basal conditions, where it associates with chromatin and participates in DNA repair. However, cytoplasmic staining may also be observed depending on cell type, fixation conditions, and cellular state, reflecting dynamic protein distribution and non-DNA-bound pools. This XRCC5 Antibody for IF enables clear visualization of both nuclear enrichment and cytoplasmic signal, supporting detailed interpretation of protein localization in single cells.
The rabbit polyclonal XRCC5 antibody supports strong performance in fluorescence microscopy and confocal imaging, where signal clarity and spatial resolution are essential. In these applications, XRCC5 staining often appears as diffuse to punctate nuclear signal with additional cytoplasmic distribution, allowing researchers to assess changes in localization under conditions such as DNA damage, cell cycle progression, or cellular stress. The ability to distinguish nuclear versus cytoplasmic XRCC5 signal makes this antibody particularly useful for studies focused on protein trafficking, chromatin association, and intracellular redistribution.
XRCC5 is a member of the DNA repair protein family and functions in coordination with DNA-dependent protein kinase to facilitate DNA end joining. Its defined nuclear role combined with dynamic intracellular distribution makes it well suited for immunofluorescence-based analysis of spatial protein behavior. XRCC5 Antibody for IF provides a robust tool for detecting Ku80 expression and visualizing its localization within cells, supporting research that depends on accurate interpretation of subcellular staining patterns.
Titration of the XRCC5 Antibody for IF / Ku80 Immunofluorescence Antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 424-450 from the human protein was used as the immunogen for this XRCC5 Antibody for IF / Ku80 Immunofluorescence Antibody.
Aliquot the XRCC5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Ku80 antibody, XRCC5 immunofluorescence antibody, Ku80 IF antibody, XRCC5 nuclear staining antibody, Ku DNA repair protein antibody
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
