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Home >> Antibodies >> XIAP Antibody

XIAP Antibody (F49444)

  Catalog No Formulation Size Price (USD)  
Image F49444-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49444-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of XIAP antibody and Ramos lysate. Expected/observed molecular weight ~57 kDa.
Western blot testing of XIAP antibody and mouse liver lysate. Expected/observed molecular weight ~57 kDa.
IHC analysis of FFPE human colon carcinoma tissue stained with XIAP antibody
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P98170
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This XIAP antibody is available for research use only.
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Description

BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.

Application Notes

Titration of the XIAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this XIAP antibody.

Storage

Aliquot the XIAP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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