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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Important in the maintenance of hemostasis, von Willebrand Factor promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. [UniProt]
Titration of the vWF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This vWF antibody was produced from a mouse immunized with human recombinant protein.
Aliquot the vWF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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