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  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Home >> Antibodies >> Viperin Antibody

Viperin Antibody (N1126)

  Catalog No Formulation Size Price (USD)  
N1126-100UG 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 275

N1126-25UG 0.5 mg/ml antibody in PBS with 0.1 mg/ml BSA (US source) and 0.05% sodium azide 25 ug 129
Western blot testing of human samples using Viperin antibody at 3ug/ml.
Species Reactivity Human, Mouse, Rat, Dog
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Protein A affinity chromatography purified antibody
Buffer 1X PBS, pH 7.4
Gene ID 91543
Applications Western blot : 3-6ug/ml
Limitations This Viperin antibody is available for research use only.
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Description

Viral infection induces the interferon (IFN) response which triggers the production of an array of anti-viral proteins. Viperin (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is expressed in response to IFN-b binding to the IFN receptor, inducing the formation of the IFN-stimulated gene factor 3 complex which then binds to the Viperin promoter. It inhibits many DNA and RNA viruses through a diverse range of mechanisms and is involved in the PRR-mediated innate immune response. Viperin has been shown to be produced in response to TLR3 and TLR4 activation, but not TLR2 and TLR5. It may be involved in the TLR7 and TLR9-induced production of type I IFN by plasmacytoid dendritic cells (pDCs).

Application Notes

Provided assay concentrations are suggestions only, Viperin antibody titration may be required for optimal results.

Immunogen

A recombinant protein fragment from the N-terminal region of human Viperin was used as the immunogen for this antibody.

Storage

Aliquot the Viperin antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycle.

Alternate Names

Virus inhibitory protein endoplasmic reticulum associated interferon inducible, Virus inhibitory protein

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