- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
VIL1 Antibody / Enterocyte Functional Marker Antibody [clone rVIL1/8336] (V4947)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V4947-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
|
V4947-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
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V4947SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG1, kappa |
| Clone Name | rVIL1/8336 |
| Purity | Protein A/G affinity |
| UniProt | P09327 |
| Localization | Cytoplasm, Cell Surface |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT |
| Limitations | This VIL1 antibody is available for research use only. |
|
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Villin-1 (VIL1) is a key actin-associated protein expressed in absorptive epithelial cells, where it contributes to the functional organization of the intestinal surface. VIL1 Antibody / Enterocyte Functional Marker Antibody (clone rVIL1/8336) is positioned to detect Villin in studies focused on epithelial physiology and absorptive function. VIL1 antibody, also referred to as Villin-1 antibody or Villin antibody, is widely used in research examining enterocyte biology and intestinal epithelial activity.
This VIL1 Antibody / Enterocyte Functional Marker Antibody is differentiated by its focus on functional enterocyte biology rather than structural identity or differentiation status. While Villin is commonly used as a differentiation marker, its biological significance extends to maintaining the specialized architecture required for nutrient absorption and epithelial function. Villin contributes to the stability and adaptability of actin networks that support absorptive processes at the luminal surface.
Enterocytes rely on tightly regulated cytoskeletal organization to maintain efficient transport, membrane turnover, and barrier function. Villin plays an important role in these processes by modulating actin filament dynamics in a way that supports epithelial function under varying physiological conditions. This includes adaptation to dietary changes, epithelial renewal, and maintenance of intestinal homeostasis.
For researchers, this VIL1 antibody is particularly valuable in studies of intestinal physiology, epithelial absorption mechanisms, and enterocyte functional states, where Villin expression reflects active epithelial function rather than simply lineage identity. Clone rVIL1/8336 provides a tool aligned with functional and physiological investigations of intestinal epithelium.
Optimal dilution of the VIL1 Antibody / Enterocyte Functional Marker Antibody should be determined by the researcher.
A recombinant partial protein sequence (within amino acids 600-700) from the human protein was used as the immunogen for the VIL1 Antibody / Enterocyte Functional Marker Antibody.
Aliquot the VIL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Villin-1 antibody, VIL1 enterocyte marker antibody, Villin absorptive cell marker antibody, Villin intestinal function antibody
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