- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
VEGFR2 Antibody / VEGF Receptor 2 / KDR [clone DC101] (V8272)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
V8272-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 519 | |
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V8272-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 229 | |
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V8272SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 519 |
|
| Availability | 1-3 business days |
| Species Reactivity | Mouse |
| Format | Purified |
| Clonality | Monoclonal (rat origin) |
| Isotype | Rat IgG1, kappa |
| Clone Name | DC101 |
| Purity | Protein G affinity chromatography |
| UniProt | P35918 |
| Applications | Western blot (Non-reducing) : 2-5ug/ml Blocks binding of VEGF to VEGF-R2 : Inhibits VEGF-induced signalingformat) : Blocks tumor growth in mice : |
| Limitations | This VEGFR2 antibody is available for research use only. |
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This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Optimal dilution of the VEGFR2 antibody should be determined by the researcher.
Recombinant full-length Mouse VEGFR2 protein was used as the immunogen for this VEGFR2 antibody.
Store the VEGFR2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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