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Home >> Antibodies >> VEGFD Antibody

VEGFD Antibody (R30396)

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  Catalog No Formulation Size Price (USD)  
Image R30396 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of VEGFD antibody and Lane 1: SW620; 2: COLO320; 3: 6T-CEM; 4: HT1080 cell lysate. Expected molecular weight: 40-53 kDa (pro-form), ~21 kDa (mature/active form).
Western blot testing of VEGFD antibody and Lane 1: SW620; 2: COLO320; 3: 6T-CEM; 4: HT1080 cell lysate. Expected molecular weight: 40-53 kDa (pro-form), ~21 kDa (mature/active form).
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt O43915
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
Limitations This VEGFD antibody is available for research use only.
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Description

C-fos induced growth factor(FIGF)(or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor(PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. Analyzing by Northern blotting, Yamada et al.(1997) symbolized VEGFD, was expressed as a 2.2-kb transcript with highest expression in lung, heart, small intestine, and fetal lung, and lower levels in skeletal muscle, colon, and pancreas. And Achen et al.(1998) concluded that VEGFD was most closely related to VEGFC by virtue of the presence of N- and C-terminal extensions that were not found in other VEGF family members. Stacker et al.(2001) showed that VEGFD can induce tumor angiogenesis through VEGFR2 and tumor lymphangiogenesis through VEGFR3, whereas VEGF, which does not activate VEGFR3, induces only tumor angiogenesis.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the VEGFD antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the middle region of human VEGFD (VIDEEWQRTQCSPRE) was used as the immunogen for this VEGFD antibody (100% homologous human, mouse and rat).

Storage

After reconstitution, the VEGFD antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all VEGF antibodies

   2.   View all VEGFD antibodies

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