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Home >> Antibodies >> VEGFA Antibody

VEGFA Antibody (F49566)

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  Catalog No Formulation Size Price (USD)  
Image F49566-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49566-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of VEGFA antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the VEGFA gene (2). Expected molecular weight 19~22 kDa (monomer) and 38~44 kDa (dimer). Banding may appear larger than predicted due to glycosylation.
Western blot analysis of VEGFA antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the VEGFA gene (2). Expected molecular weight 19~22 kDa (monomer) and 38~44 kDa (dimer). Banding may appear larger than predicted due to glycosylation.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P15692
Applications Western blot : 1:1000
Limitations This VEGFA antibody is available for research use only.
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Description

VEGFA is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGFA have been associated with proliferative and nonproliferative diabetic retinopathy.

Application Notes

Titration of the VEGFA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 66-95 from the human protein was used as the immunogen for this VEGFA antibody.

Storage

Aliquot the VEGFA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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