- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
VEGF Antibody Clone VG1 / Vascular Endothelial Growth Factor Antibody [clone VG1] (V8154)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V8154-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 559 | |
|
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V8154-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 259 | |
|
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V8154SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | VG1 |
| Purity | Protein G affinity chromatography |
| UniProt | P15692 |
| Applications | ELISA (order BSA-free Format For Coating) : Immunohistochemistry (FFPE) : 2-4ug/ml |
| Limitations | This VEGF Antibody Clone VG1 / Vascular Endothelial Growth Factor Antibody is available for research use only. |
|
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VEGF Antibody Clone VG1 / Vascular Endothelial Growth Factor Antibody recognizes vascular endothelial growth factor (VEGF), a secreted signaling protein that plays a central role in angiogenesis, vascular permeability, and endothelial cell regulation. VEGF binds specific tyrosine kinase receptors on endothelial cells, primarily VEGFR1 and VEGFR2, activating pathways that promote endothelial proliferation, migration, survival, and new blood vessel formation. These processes are essential for normal vascular development and tissue repair but also contribute to pathological angiogenesis associated with cancer and other diseases.
VEGF is one of the most extensively studied regulators of tumor angiogenesis. Hypoxic tumor environments stimulate VEGF expression through HIF-dependent signaling pathways, leading to increased vascular growth that supports tumor expansion and metastatic progression. Detection of VEGF expression by immunohistochemistry is widely used in cancer research to evaluate angiogenic activity and changes within the tumor microenvironment. VEGF Antibody Clone VG1 is a well-established monoclonal antibody that has been referenced in numerous publications studying VEGF expression across cancer, vascular biology, and disease research models.
In addition to oncology research, VEGF signaling contributes to cardiovascular biology, inflammatory responses, wound healing, and tissue remodeling. Regulation of VEGF expression influences endothelial barrier function, vascular remodeling, and communication between endothelial cells and surrounding tissues. Because VEGF is a key mediator connecting hypoxia responses with vascular growth, antibodies targeting VEGF remain important tools for studying angiogenesis-related pathways and disease mechanisms.
For additional information about VEGFA biology, validated applications, and related products, learn more about our VEGF Antibody, an Angiogenesis Growth Factor Antibody for investigating endothelial signaling, tumor angiogenesis, vascular remodeling, and VEGF-mediated growth factor pathways.
Optimal dilution of the VEGF Antibody Clone VG1 / Vascular Endothelial Growth Factor Antibody should be determined by the researcher.
Recombinant human protein was used as the immunogen for the VEGF antibody.
Store the VEGF antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
VEGFA Antibody, Vascular Endothelial Growth Factor A Antibody, VEGF-A Antibody, Vascular Permeability Factor Antibody, VPF Antibody, Angiogenesis Factor Antibody
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