- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
VCL Antibody / Vinculin (F54927)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
F54927-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 439 | |
|
|
F54927-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 205 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P18206 |
| Localization | Cytoplasmic |
| Applications | Western Blot : 1:500-1:1000 Immunohistochemistry (FFPE) : 1:10-1:50 |
| Limitations | This VCL antibody is available for research use only. |
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VCL/Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia.
Learn more about focal adhesion biology and vinculin research by visiting our Vinculin Antibody / Focal Adhesion Protein Antibody page.
The stated application concentrations are suggested starting points. Titration of the VCL antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 12-39 from the human protein was used as the immunogen for the VCL antibody.
Aliquot the VCL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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