- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
VCL Antibody / Vinculin (F54927)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54927-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F54927-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P18206 |
| Localization | Cytoplasmic |
| Applications | Western blot : 1:500-1:1000 Immunohistochemistry (FFPE) : 1:10-1:50 |
| Limitations | This VCL antibody is available for research use only. |
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VCL/Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia.
The stated application concentrations are suggested starting points. Titration of the VCL antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 12-39 from the human protein was used as the immunogen for the VCL antibody.
Aliquot the VCL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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