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Home >> Antibodies >> VANGL2 Antibody

VANGL2 Antibody (F53408)

  Catalog No Formulation Size Price (USD)  
Image F53408-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F53408-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Western blot testing of VANGL2 antibody at 1:2000 dilution + DU145 lysate; Predicted molecular weight ~60 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9ULK5
Applications Western blot : 1:2000
Limitations This VANGL2 antibody is available for research use only.
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Description

Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).

Application Notes

Titration of the VANGL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This VANGL2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-410 amino acids from human VANGL2.

Storage

Aliquot the VANGL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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