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Home >> Antibodies >> Urokinase Antibody

Urokinase Antibody (F51093)

  Catalog No Formulation Size Price (USD)  
Image F51093-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F51093-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of Urokinase antibody and A2058 lysate
Western blot analysis of Urokinase antibody and A2058 lysate
Western blot analysis of Urokinase antibody and mouse brain tissue lysate
IHC analysis of FFPE human prostate carcinoma tissue stained with Urokinase antibody
Urokinase antibody flow cytometric analysis of A2058 cells (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P00749
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Flow Cytometry : 1:10-1:50
Limitations This Urokinase antibody is available for research use only.
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Description

PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders. PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin. The protein is found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A. Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain. The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis. Structurally, PLAU contains 1 EGF-like domain and 1 kringle domain.

Application Notes

Titration of the Urokinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 60-90 from the human protein was used as the immunogen for this Urokinase antibody.

Storage

Aliquot the Urokinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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