UPK1B Antibody / Membrane Tetraspanin-like Protein Antibody [clone UPK1B/3081] (V8152)

UPK1B Antibody for IHC. Immunohistochemistry analysis of Uroplakin 1B / UPK1B antibody in human urothelial carcinoma tissue using clone UPK1B/3081. FFPE sections show strong HRP-DAB brown membranous staining in tumor epithelial cells with a uniform cell surface distribution, consistent with plasma membrane localization of this tetraspanin-like protein. This Membrane Tetraspanin-like Protein Antibody highlights the organized membrane pattern and protein clustering characteristic of UPK1B in urothelial tumor cells. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 minutes followed by cooling prior to staining.

UPK1B Antibody for IHC. Immunohistochemistry analysis of Uroplakin 1B / UPK1B antibody in human urothelial carcinoma tissue using clone UPK1B/3081. FFPE sections demonstrate strong HRP-DAB brown membranous staining in tumor epithelial cells with well-defined cell borders, consistent with localization of this tetraspanin-like membrane protein at the plasma membrane. This Membrane Tetraspanin-like Protein Antibody highlights the characteristic membrane organization and cell surface pattern of UPK1B in urothelial tumor cells. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 minutes followed by cooling prior to staining.

UPK1B Antibody for IHC. Immunohistochemistry analysis of Uroplakin 1B / UPK1B antibody in human urothelial carcinoma tissue using clone UPK1B/3081. FFPE sections show strong HRP-DAB brown membranous staining outlining tumor epithelial cells with a cohesive cell surface pattern, consistent with plasma membrane localization of this tetraspanin-like protein. This Membrane Tetraspanin-like Protein Antibody highlights the organized membrane architecture and surface distribution of UPK1B in urothelial tumor cells. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 minutes followed by cooling prior to staining.

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using UPK1B antibody (clone UPK1B/3081). These results demonstrate the foremost specificity of the UPK1B/3081 mAb.
Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

SDS-PAGE analysis of purified, BSA-free UPK1B antibody as confirmation of integrity and purity.