- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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CD87 Antibody recognizes CD87, also known as urokinase plasminogen activator receptor (uPAR) or PLAUR, a GPI-anchored cell surface receptor involved in immune cell function, protease regulation, and extracellular matrix remodeling. CD87 binds urokinase-type plasminogen activator (uPA), promoting localized plasmin generation at the cell membrane and supporting processes such as cell migration, adhesion, and tissue remodeling. Through interactions with integrins, vitronectin, and other signaling molecules, CD87 influences cellular communication with the surrounding microenvironment. CD87 Antibody is commonly used to study immune cell activation, inflammatory responses, and uPAR-mediated signaling pathways.
CD87 expression is found on multiple immune cell populations, including monocytes, macrophages, activated neutrophils, and other leukocyte subsets. In immunology research, CD87 is frequently investigated as a marker associated with myeloid cell activation, leukocyte trafficking, and inflammatory responses. Increased PLAUR expression has also been reported in many tumor types, where uPAR contributes to cancer cell migration, extracellular matrix degradation, tumor invasion, and metastatic progression.
This CD87 Antibody is particularly useful for researchers studying immune cell biology, where detection of cell surface CD87/uPAR expression helps characterize activated immune populations. The receptor's involvement in both inflammatory signaling and tumor microenvironment remodeling makes CD87 an important target across immunology, oncology, and cell biology research. Studies of soluble uPAR (suPAR), generated through receptor cleavage, have further highlighted the importance of PLAUR biology in chronic inflammation, immune activation, and disease progression.
For additional information about PLAUR/uPAR biology, validated applications, and related products, learn more about our uPAR Antibody, a Cell Invasion Receptor Antibody for investigating extracellular matrix remodeling, cancer cell migration, tumor invasion, and protease-mediated signaling.
Optimal dilution of the CD87 Antibody / uPAR should be determined by the researcher.
Amino acids TKSGCNHPDLDVQYRS were used as the immunogen for the CD87 / uPAR antibody.
After reconstitution, the CD87 / uPAR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
uPAR Antibody, PLAUR Antibody, Urokinase Receptor Antibody, uPA Receptor Antibody, Urokinase Plasminogen Activator Receptor Antibody, Cell Surface CD87 Antibody
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