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Home >> Antibodies >> UBR2 Antibody

UBR2 Antibody [clone 2G11] (RQ6293)

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  Catalog No Formulation Size Price (USD)  
Image RQ6293 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 449
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UBR2 Antibody WB. Western blot testing of human 1) HEK293, 2) Jurkat and 3) K562 cell lysate with UBR2 antibody. Predicted molecular weight ~202 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Host Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a
Clone Name 2G11
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q8IWV8
Applications Western Blot : 1-2ug/ml
Limitations This UBR2 antibody is available for research use only.
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Description

UBR2 Antibody specifically detects E3 ubiquitin-protein ligase UBR2, an enzyme that in humans is encoded by the UBR2 gene. It is mapped to 6p21.1. This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.

Researchers investigating ubiquitin-mediated protein degradation, proteostasis signaling, and N-end rule pathway regulation may also be interested in our UBR2 Antibody / N-End Rule Pathway Regulator page featuring validated tools for immunofluorescence, flow cytometry, immunohistochemistry, and protein microarray specificity analysis.

Application Notes

Optimal dilution of the UBR2 antibody should be determined by the researcher.

Immunogen

A human recombinant partial protein (amino acids Q10-A664) was used as the immunogen for the UBR2 antibody.

Storage

After reconstitution, the UBR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Alternate Names

UBR2 N-end rule antibody, Ubiquitin protein ligase E3 component n-recognin 2 antibody, Protein degradation pathway antibody, Proteostasis regulator antibody, Ubiquitin pathway antibody

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