- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
UBA3 Antibody / Ubiquitin-activating enzyme 3 / UBE1C [clone 28U91] (RQ8574)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ8574 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ug | 439 |
|
| Availability | 1-3 days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | 28U91 |
| Purity | Affinity chromatography |
| UniProt | Q8TBC4 |
| Applications | Western Blot : 1:500-1:2000 |
| Limitations | This UBA3 antibody is available for research use only. |
|
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NEDD8-activating enzyme E1 catalytic subunit (UBA3) is the catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression. [UniProt]
Optimal dilution of the UBA3 antibody should be determined by the researcher.
A synthetic peptide from human NEDD8-activating enzyme E1 catalytic subunit protein was used as the immunogen for the UBA3 antibody.
Store the UBA3 antibody at -20oC.
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