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Home >> Antibodies >> Type I Cytokeratin Antibody / Acidic / LMW

Type I Cytokeratin Antibody / Acidic / LMW [clone KRTL/7784R] (V4498)

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  Catalog No Formulation Size Price (USD)  
Image V4498-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4498-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4498SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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IHC staining of FFPE human prostate carcinoma tissue with Type I Cytokeratin antibody (clone KRTL/7784R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human prostate carcinoma tissue with Type I Cytokeratin antibody (clone KRTL/7784R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name KRTL/7784R
Purity Protein A/G affinity
UniProt Q7Z794
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Limitations This Type I Cytokeratin antibody is available for research use only.
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Description

This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.

The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation.

Application Notes

Optimal dilution of the Type I Cytokeratin antibody should be determined by the researcher.

Immunogen

A synthetic peptide corresponding to human Type I Cytokeratin proteins was used as the immunogen for the Type I Cytokeratin antibody.

Storage

Aliquot the Type I Cytokeratin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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