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  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Home >> Antibodies >> TTF-1 Antibody / NKX2.1

TTF-1 Antibody / NKX2.1 (F40894)

  Catalog No Formulation Size Price (USD)  
F40894-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329

F40894-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
TTF-1 antibody western blot analysis in HeLa lysate.
TTF-1 antibody flow cytometric analysis of HeLa cells (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P43699
Applications Western blot : 1:1000
Flow Cytometry : 1:10-1:50
Limitations This TTF-1 antibody is available for research use only.
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Description

This gene encodes a protein initially identified as a thyroid-specific transcription factor. NKX2.1/TTF-1 binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Application Notes

Titration of the TTF-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 2-1 from the human protein was used as the immunogen for this TTF-1 antibody.

Storage

Aliquot the TTF-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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